This lecture extends the basic concepts introduced in the course "Adaptive Materials and Smart Structures" and integrates them in order to build up complete adaptive systems. The control theory will be extended to the control of multiple-input/multiple-output systems and the application of state-space based design methods. In practical exercises an introduction to system identification methods and structural control will be given. Furthermore the problem of fatigue will be considered with a special focus on adaptive materials. Finally, typical examples of adaptive systems (adaptive wing, adaptive rotorblade, structural-acoustic control) will be shown.